Marijuana Users Require More Sedatives, Preliminary Study Reports

Mark A. Twardowski, DO

Mark A. Twardowski, DO

A small study out of a western Colorado endoscopy center has broken ground in reporting that patients who regularly use marijuana require significantly greater amounts of sedatives for endoscopic procedures.

Mark A. Twardowski, DO, an osteopathic internal medicine physician who practices at Western Medical Associates in Grand Junction, Colorado, began noticing that some of his patients required greater levels of fentanyl, midazolam, or propofol for sedation before a procedure.

“Marijuana has been recreationally legal in Colorado for several years and in doing endoscopy procedures we thought we were seeing a trend that folks who were using marijuana regularly were requiring more medication to sedate them for the procedures,” Twardowski told MD Magazine®.

He and his colleagues, Margaret M. Link, MSN, RN, CRNI, and Nicole M. Twardowski, BS, found that patients reporting regular marijuana use, whether smoked or consumed, required substantially more sedative medication. That

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