However, the improvement does not appear to result from a dampening down of the underlying inflammatory process, as previously thought.
“Cannabis has been used for centuries to treat a wide range of medical conditions, and studies have shown that many people with Crohn’s disease use cannabis regularly to relieve their symptoms,” said lead researcher Dr Timna Naftali, speaking at UEG Week 2018 in Vienna.
“It has always been thought that this improvement was related to a reduction in inflammation in the gut and the aim of this study was to investigate this.”
Forty-six people with moderately severe Crohn’s disease were recruited for the study, and randomised to receive eight weeks of treatment with either CBD oil containing 15 per cent cannabidiol and four per cent tetrahydrocannabinol, or placebo.
Symptom severity and quality of life were measured before, during, and after treatment, while gut inflammation was also assessed.
After eight weeks of treatment, the group receiving