Evidence remains insufficient to determine if marijuana use has any impact — good or bad — on cardiovascular disease risk, researchers stated.
In a systematic review of 24 observational studies, six suggested a metabolic benefit associated with marijuana use, but all six were cross sectional. A single prospective cohort study with a more robust analytic design found no evidence of a metabolic benefit. For all but one risk factor or outcome evaluated, the quality of evidence was rated as “insufficient,” according to Divya Ravi, MD, MPH, of the Wright Center for Graduate Education in Scranton, Pennsylvania, and colleagues.
The evidence regarding a link between marijuana use and obesity was rated as “low,” with one well-designed study and two cross-sectional studies showing no link, they wrote in the Annals of Internal Medicine.
Ravi’s group reviewed studies examining adult cannabis use and vascular risk factors such as hyperglycemia, diabetes,
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