According to the World Health Organization, 350 million people across the globe suffer from depression.
While widely seen as the scourge of 21st life, and seemingly on the rise, awareness around the condition is, thankfully, greater than ever.
The most common treatments for depression, and associated mood disorders, are antidepressants and psychotherapy – often the two are combined.
However, researchers across the world continue to explore alternative pharmaceutical options, with clinical trials frequently on the go.
Below, NetDoctor takes a look at five of the most surprising – and controversial – treatments being explored by the academic and medical communities.
More commonly regarded as an illicit party drug, many medical experts believe ketamine could be a life-changing option for those with deep depression or suffering suicidal thoughts.