Animal Study Suggests Cannabis Might Reverse Brain Aging

Couple on porch outsideIn a study published in the journal Nature Medicine, tetrahydrocannabinol (THC)—the active ingredient in cannabis—reversed age-related cognitive decline in mice.

Mice, like humans, experience cognitive changes such as memory loss as they age. Researchers were able to use cannabis to help older mice regress to a state similar to mice who were only a few months old. If humans experience similar results with the use of cannabis, then the drug may eventually yield a treatment for dementia. However, not all studies of rodents have translated into similar results for humans.

Cannabis Reverses Age-Related Cognitive Changes in Mice

Previous research has found the endocannabinoid system (ECS), a group of receptors that regulate a variety of physiological processes, declines with age. The ECS also contains receptors that bind to THC, marijuana’s active ingredient.

To test how THC might affect age-related changes

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