What is Glaucoma?
The optic nerve carries signals from the eye to the brain, resulting in vision. Glaucoma can lead to damage of the optic nerve, and untreated, long-standing glaucoma can lead to blindness. In many cases, this damage is caused by an increase in pressure within the eye (intra-ocular pressure), resulting from abnormalities with the amount of fluid in the front portion of the eye, called “aqueous humor“, which is produced by a part of the eye called the ciliary body.
Pressure in the eye builds either due to (1) a decrease in aqueous humor clearance due to a blockage in the outflow space, or (2) an increase in the amount of aqueous humor in the front eye compartment. For example, when blood pressure is high, the pressure in the capillaries of the ciliary body may also be high, leading to increased production by ultrafiltration/decreased